Nanoscale hydroxyapatite ( nano-HAP) is widely used in repairing of bone tissue and enamel defects because of its excellent biological compatibility, while it has hardly achieved any significant progress in the remineralization of dentin collagen fibers. 纳米级的羟基磷灰石(hydroxyapatite,HAP)以其良好的生物性能而广泛应用于骨组织和牙釉质缺损的修复,但是其在牙本质胶原纤维上的矿化研究仍未获得明显进展。